Phytopharmacological Profile of Elephantopus scaber

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Sesquiterpene lactones from Elephantopus scaber

The ethanolic and acetone extracts of the whole plant of Elephantopus scaber were found to contain ethyl hexadecanoate, ethyl-9,12-octadecadienoate, ethyl-(Z)9-octadecenoate, ethyl octadecanoate, lupeol, stigmasterol, stigmasterol glucoside, deoxyelephantopin (1) and two new germacranolide sesquiterpene lactones named 17,19-dihydrodeoxyelephantopin (2) and iso-17,19-dihydrodeoxyelephantopin (3)...

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ANTIBACTERIAL STUDIES ON LEAF EXTRACT OF ELEPHANTOPUS SCABER Linn

Methanolic extract of Elephantopus scaber Linn was investigated for its antibacterial activity against Staphylococcus aureus (NCIM - 2079), Escherichia coli (NCIM-2067), Bacillus subtilis (NCIM-2063), Pseudomonas aeruginosa (NCIM-2036), Proteus vulgaris (NCIM-2027) at 100 μg/disc by using disc diffusion method. The extract showed significant anti bacterial activity and were compared to chloramp...

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Hepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice

Elephantopus scaber has been traditionally used as liver tonic. However, the protective effect of E. scaber on ethanol-induced liver damage is still unclear. In this study, we have compared the in vivo hepatoprotective effect of E. scaber with Phyllanthus niruri on the ethanol-induced liver damage in mice. The total phenolic and total flavanoid content of E. scaber ethanol extract were determin...

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Antioxidant and Wound Healing Activity of Polyherbal Fractions of Clinacanthus nutans and Elephantopus scaber

Elephantopus scaber and Clinacanthus nutans are traditionally used as wound healing herb. The objective of the present study is to develop a new polyherbal formulation, by comparison, the herbal combination of Elephantopus scaber and Clinacanthus nutans as an in vitro antioxidant activity with their individual herbal activity followed by fractionation of polyherbal formulation for in vivo wound...

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Bioactivities of Compounds from Elephantopus scaber, an Ethnomedicinal Plant from Southwest China

Elephantopus scaber is an ethnomedicinal plant used by the Zhuang people in Southwest China to treat headaches, colds, diarrhea, hepatitis, and bronchitis. A new δ -truxinate derivative, ethyl, methyl 3,4,3',4'-tetrahydroxy- δ -truxinate (1), was isolated from the ethyl acetate extract of the entire plant, along with 4 known compounds. The antioxidant activity of these 5 compounds was determine...

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ژورنال

عنوان ژورنال: Pharmacologia

سال: 2014

ISSN: 2044-4648

DOI: 10.5567/pharmacologia.2014.272.285